System lock when trying to boiot from USB

I have managed to configure the bios to boot from USB. Although, when I try to boot from usb which is configured to use WINPE the system locks and both the keyoboard and mouse does not respond. . I have mounted the usb 3 drivers and also network drivers via the USB. Although, I am still getting the same issue.

Do you know what I need to do in order to get this to work.

thanks.